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Suppose you start up a small independent grocery store, and during the first year, the rent on the building costs you $100,000 The second year, the landlord raises it to $200,000 The third year, it goes up to $300,000, and so on, rising by $100,000 every year You could raise prices, but beyond a certain point, the customers wouldn t pay To cover the rising rent, you d have to work harder, stay open longer, and sell a lot more groceries Something similar has happened to game development in the last 20 years It now costs 20 times as much, or more, to develop a videogame than it did two decades ago Publishers can t cover that by raising the price of games 20 times; the players won t pay it Instead, the publishers have to work harder and sell more games Rising development costs may mean more jobs for developers, but it s hard on the publishers who pay those costs This, in turn, affects how they work and what kinds of games they choose to produce

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Section I includes s 1 3, Useful Facts for the Wards These chapters include common laboratory values and essential knowledge of female anatomy and commonly performed procedures in obstetrics and gynecology Sections II and III are divided into several chapters that contain thorough and highyield material on obstetrics and gynecology It has been our goal to fulfill the third-year learning objectives recommended by the American Professors of Gynecology and Obstetrics (APGO) and the American College of Obstetrics and Gynecology (ACOG) Section IV is dedicated to Women s Health Issues, which contains information on domestic violence, sexual assault, and ethics and law Section V of this book provides the reader with many clinical vignettes that students may face on the USMLE Step 2 CK and on the wards This section encourages students to apply their knowledge of obstetrics and gynecology to relevant clinical scenarios Topics are covered in a question and answer format with buzz words highlighted in bold for each response This format is designed for rapid review during the clerkship and before exams Furthermore, we have included questions that require students to think about a problem in a logical and clinically appropriate manner It is our hope that this book will supplement topics learned in the clinical setting and will facilitate success on the clerkship shelf exam and the USMLE Step 2 CK We also hope to stimulate interest in the fascinating fields of obstetrics and gynecology through exposure to some of the exciting clinical cases that are typical of this field

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nerve roots and becomes latent in the dorsal root ganglion Reactivation: can occur at any interval when the virus travels back down the sensory nerve This can either cause a mucocutaneous outbreak (recurrence) or sometimes no symptoms may be detected What is the strongest risk factor for genital HSV infection What clinical presentation is suggestive of primary genital herpes A large number of lifetime sex partners A prodrome of 2 24 hours characterized by localized/regional burning and pain Systemic symptoms including fever, malaise, and bilateral inguinal lymphadenopathy Grouped vesicles, uniform in size, mixed with multiple, shallow, severely tender ulcers around the vulva, perineum, and perianal area are pathognomonic Cervical lesions are also common and cause intermittent bleeding and vaginal discharge Dysuria and urinary retention syndromes may occur because of contact with urethral and vulvar ulcers Are all primary outbreaks clinically symptomatic No 70 80% of infected persons have unrecognized symptoms or completely asymptomatic infections; therefore, transmission of this virus can be high and unrecognized Type-specific viral cultures (highest sensitivity and specificity; highest yield if done early when you can attain more vesicle fluid) Direct fluorescence antibody test Type-specific serologic testing (best for those with a questionable hx, subclinical infection, or suspicion of a false-negative viral culture) Tzanck smears Polymerase chain reaction (PCR) What is the presentation of a secondary outbreak They vary widely in their frequency, are milder and shorter in duration,

It s no secret that publishers have become more and more conservative over the years You just can t take the kinds of risks with $2 million that you could with $100,000 They re unwilling to fund unusual, quirky games that might not make any money Not every game needs to be a smash hit, but every game needs to be a steady, reliable seller

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